Five centuries after her time, Isabel of Castile tells her story. The story of a woman who was Queen and exercised Power in Renaissance Europe. The Queen who created the Modern Age and made the Discovery of America possible is contrasted with the woman who suffers from loneliness and incomprehension. Isabel of Castile is an emblematic, controversial figure who arouses irreconcilable passions that magnify her or, on the contrary, disqualify her.